Leah Sabin

Leah Sabin

Company: Regeneron

Job title: Executive Director - Genetic Medicines


Demonstrating Successful Blood-Brain Barrier Penetration of AAVs in Rodent Models to Optimize Gene Delivery for Neurological Disorders 12:00 pm

Leveraging in vivo screening approaches to identify Transferrin Receptor-specific antibodies to support BBB crossing of conjugated AAVs Utilizing specific capsid mutations to abolish natural glycan binding and minimize peripheral targeting of undesired tissues Comparing ICV and IV route for AAV targeting to the mouse brainRead more

day: Conference Day One

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