Bryn Martin
Company: Alcyone Therapeutics
Job title: Vice President of Research, Drug Delivery, and CSF Sciences
Seminars:
Chair’s Closing Remarks & End of Conference 3:45 pm
day: Conference Day Two
Chair’s Opening Remarks 8:50 am
day: Conference Day Two
Panel Discussion: Evaluating In Vivo & In Vitro Systems to Effectively Model Transportation of Neurological & Neuro-Oncology Drugs to the CNS 8:30 am
From microfluidics to BBB chips to organoids: which in vitro systems show greatest translational relevance? What must be improved in in vivo recapitulations of BBB to achieve reliable drug read outs that can be used in human trials? How can we achieve greater confidence in in vitro systems to replicate human BBB biology? How can…Read more
day: Conference Day One
Enhancing Therapeutic Distribution Beyond Areas Adjacent to the Site of Intra-CSF or Intranasal Administration 2:05 pm
To maximize potential of intra-CSF or intranasal delivery, it is important to overcome barriers imposed by neuroanatomy and CSF flow to aid diffusion to deeper brain regions. • How can we deepen exposure to concentrated regions, such as the mid brain and striatum, following direct dosing into the CSF or nasal cavity? • Which cases…Read more
day: Pre-Conference Track 2 PM