11.00 Developing Clinically Translatable Capsids with Enhanced CNS Tropism Through Human Receptor-Targeted Engineering
Time: 11:00 am
day: Day Two Track 1 AM
Details:
- Outlining the rational design: genetically fusing a TFR1-targeting moiety to an AAV capsid
- Demonstrating efficient CNS transduction specifically in humanized mouse models expressing TFR1
- Highlighting their translatability and clinical applications
