Pawel Stocki

Company: Ossianix Inc

Job title: Vice President of Research

Seminars:

12.00 Presenter Q+A & Audience Discussion 12:00 pm

What do we mean by 'next generation' antibodies and how can we enhance their clinical relevance?Read more

day: Day One Track 1 AM

11.30 Overcoming Translational Challenges of Cross Reactivity to Develop a Clinically Relevant BBB-Penetrant Antibody Platform 11:30 am

Discussing the translational barriers of developing biologic-based drugs to cross the blood-brain barrier Navigating differences in BBB receptor profiles between in vivo models to ensure cross-reactivity Increasing confidence of in vivo toxicity studies to ensure safe translation to humansRead more

day: Day One Track 1 AM

Exploring Opportunities for Systemic Antisense Delivery with Receptor-Mediated BBB Shuttles 8:00 am

Due to their large size and virus-like nature eliciting immune defences, oligonucleotide therapeutics have been restricted in their ability to be delivered systemically and cross the blood-brain barrier, but what if they could be conjugated to brain-penetrating proteins and shuttled across as cargo? Push the boundaries of ASO delivery beyond intrathecal injection and uncover new…Read more

day: Pre-Conference Day