Lisa Shafer
Solutions Vice President, Product Delivery Biogen
Seminars
Wednesday 10th December 2025
Round-table Discussion: Straight to the Targett: Exploring the Role of Direct CNS Access in Modern Therapeutics to Solidify Local Administration in the Clinic
2:00 pm
Highly interactive breakout discussions designed to crowdsource solutions, share cross-functional insights, and explore the practical barriers to clinical adoption.
- What safety, procedural, or monitoring strategies are most critical to de-risk intra- CSF and other direct CNS delivery methods in clinical trials?
- How can integration between therapeutic formulation and delivery systems be optimized to accelerate approval of combination products?
Moderator Feedback & Audience Debate
Moderators will be assigned to each roundtable to facilitate discussion and collate the findings. Following the roundtable discussions, they will present back to the entire delegation and open a wider audience debate.
Wednesday 10th December 2025
Panel Discussion: Matching Mechanism to Disease – Optimizing CNS Delivery Strategies Across Indications to Enhance Treatment Efficacy & Safety
4:30 pm
- Where systemic vs. direct (e.g., IT, ICV, convection-enhanced) routes are used
- How targeting location, BBB access, and regional specificity guide decision-making
- The impact of disease stage and progression on delivery strategy
Wednesday 10th December 2025
Chair’s Opening Remarks
8:15 am
Wednesday 10th December 2025
Chair’s Closing Remarks
5:30 pm
