4:00 Developing a Translational PBPK Model to Understand Species-Related Differences in TfR-Mediated Transcytosis of Large Molecules to the Brain
Time: 4:00 pm
day: Day One PM
Details:
- Elevating understanding of the desired drug profile for efficient TfR-mediated delivery to specific brain targets Showcasing data from rats, monkeys, and human TfR knock-in mice
- Implications for applying the model to provide precise human dose projection of drugs leveraging TfR-mediated transcytosis
