11.30 Realeve: Enabling CNS Drug Delivery through On-Demand Control of the BBB
Time: 11:30 am
day: Day One Track 2 AM
Details:
- Realeve has developed the Pulsante Neurostimulator, an implantable device which can control the permeability of the BBB by relaxing and tightening tight junction proteins through on-demand stimulation of the SPG, allowing delivery of large molecule frugs including monoclonal antibodies and stem cells increasing efficacy while reducing dosing and decreasing the risk of complications
- Pulsante has been implanted in over 700 patients to date and has been successfully used to treat cluster headaches, achieving pain relief within 15 minutes in 67.1% of patients and showing disease modifying effects
- Pulsante is implanted under local anaesthesia, using a propriety, minimally invasive, surgical procedure leaving no visual scars and is powered by an external patient controller