Reviewing Recent Progress in Focused Ultrasound Technology & Broadening its Clinical Applications
Time: 1:00 pm
day: Pre-Conference Day
Details:
Focused ultrasound is being increasingly explored to enhance therapeutic uptake, by temporarily increasing blood-brain barrier permeability, to treat a range of CNS disorders, beyond glioblastoma.
Explore possibilities for further applications of focused ultrasound-mediated drug delivery to the CNS and contemplate the evidence for:
- Safe and efficacious demonstrations of microbubble-based blood-brain barrier opening, with increased uptake of therapeutic material into the CNS during ultrasound pulses
- Restoration of blood-brain barrier flow following temporary opening
- Maintaining selectivity for the therapeutic while avoiding peripheral exposure through careful timing of blood-brain barrier opening