
Aptar Pharma
Programme Partner
Aptar Pharma is an expert in nasal drug delivery, offering advanced intranasal systems and drug delivery services from design and manufacture, formulation development and clinical product manufacturing to post launch support. Our global network of GMP manufacturing sites help us accelerate and derisk drug product development, and our investments in R&D and innovation allow us to offer proven nasal drug delivery solutions to help improve patient outcomes across the globe. Aptar Pharma is part of AptarGroup, Inc.

Realeve
Innovation Partner
Realeve is a medical device company dedicated to developing innovative solutions for autonomic disorders with an initial focus on cluster headaches treartment, but with the ultimate goal of pioneering work in Blood Brain Barrier permeability. This MRI-compatible neurostimulator device (FDA breakthrough) offers ondemand stimulation of the sphenopalatine ganglion (SPG), a key nerve structure involved in autonomic disorders by regulating blood brain barrier flow/permeability. The Pulsante System has been successfully implanted in over 700 patients in the US/Europe, with promising results, including a randomized controlled trial published in The Lancet.

SHIFTBIO
Platform Partner
SHIFTBIO is pioneering next-generation therapeutics for CNS diseases with our proprietary dtBBB-Natural Nanoparticle (NNP) platform. This AI-driven, dual-mechanism shuttle is engineered to effectively penetrate the Blood-Brain Barrier, achieving efficient delivery of diverse payloads like ASO, siRNA, and enzymes directly into the brain parenchyma. Backed by our predictable NNP Design AI™ and cGMP-ready manufacturing, we accelerate the development of breakthrough therapies, shifting the paradigm of CNS drug delivery.