Christopher Kadamus
Former Executive Director of Engineering, DDCS (Delivery, Device, & Connected Solutions) Eli Lilly
Seminars
Wednesday 2nd December 2026
Panel Discussion: Aligning Patient Experience with Next-Generation Brain Delivery for Less Burdensome, Safer & More Accessible Treatments
4:15 pm
- Understanding patient and caregiver preferences on delivery route frequency and invasiveness to inform the design of brain shuttle and systemic platforms
- Evaluating tolerability safety perceptions and adherence challenges associated with next generation brain delivery approaches across real-world care settings
- Capturing patient perspectives on monitoring burden digital endpoints and treatment impact to guide clinically meaningful endpoint selection
- Identifying barriers to access and uptake of advanced CNS delivery technologies and defining strategies to ensure equitable and scalable implementation
Tuesday 1st December 2026
Integrating Systemic & Direct Delivery Approaches – Breaking Down the Silos
1:00 pm
Challenging the artificial separation between systemic and direct delivery, exploring how these complementary approaches can work in unison rather than competition to advance CNS therapeutics.
This workshop will gather experts to:
- Challenge the “invasiveness stigma” by comparing direct CNS delivery to widely accepted neurosurgical procedures like DBS electrode placement, examining why one is embraced while the other faces resistance
- Understand CSF circulation dynamics and anatomical constraints that determine when intrathecal delivery fails versus when intraventricular or cisternal approaches succeed, optimizing delivery route selection
- Design rational decision frameworks for selecting systemic versus direct delivery based on disease location, patient population, dosing frequency, and therapeutic window requirements
