Ajit D’Souza
Executive Director, Drug Delivery & Devices DDCS Eli Lilly
Ajit D’Souza, is the Executive Director of Drug Delivery and Devices at Eli Lilly and Company. He partners with internal stakeholders to define and advance Lilly’s device and delivery strategy for the emerging portfolio. He is responsible for the development of internal drug delivery and device initiatives as well as co-development of external technologies via feasibility studies to address critical unmet patient needs. Prior to Eli Lilly, Ajit served as Senior Director of drug product development, manufacturing and device development as well as a CMC leader at Kiniksa Pharmaceuticals and worked at Becton Dickinson, BD, in various leadership roles on programs of strategic importance including development of technologies and products for subcutaneous, intradermal and pulmonary delivery. Ajit earned a Ph.D. in Pharmaceutical Chemistry from the University of Kansas, a Professional Certificate in Systems Engineering from MIT xPRO and an MBA.
Seminars
- Compare direct CNS delivery and systemic administration in terms of tissue exposure and selectivity, and their impact on target-site concentration, dose, and efficacy–toxicity balance
- Assess the limitations of systemic approaches that rely on plasma pharmacokinetics as a surrogate for efficacy versus direct delivery strategies that prioritise disease-site exposure
- Evaluate adoption barriers and translational challenges for direct delivery relative to systemic modalities, including device integration and demonstration of tissue-level pharmacological advantage
- Explore how patient, clinician, and commercial perspectives shape trade-offs between invasiveness and the potential for improved efficacy and reduced toxicity through targeted delivery
