Targeted Blood Brain Barrier Opening Using Focused Ultrasound to Enable Spatially Precise CNS Drug Delivery Without Molecular Re-Engineering
1:00 pm - Thursday 3rd December 2026
- Demonstrating transient and region-specific BBB opening using microbubble-mediated focused ultrasound with reproducible safety across 300+ patients
- Enabling localized delivery of biologics, oligonucleotides and gene therapies with preserved molecular integrity and enhanced target engagement
- Quantifying biodistribution shifts and pharmacodynamic effects following ultrasound-mediated BBB modulation in oncology and neurodegeneration
- Positioning focused ultrasound within the broader CNS delivery toolkit alongside intrathecal dosing and receptor-mediated transport approaches
