Redefining BBB Penetration: Engineering Small Molecules for Active CNS Delivery via Uptake Transporters
Time: 2:40 pm
day: Day One - Afternoon - Track A
Details:
- Harnessing endogenous uptake transporters for targeted brain delivery
- Designing integrated, linker-free small molecules for improved specificity and stability
- Using animal studies, tissue distribution analysis, and transporter expression atlases to predict and minimize off-target effects in non-CNS tissues such as the heart and liver
