Optimizing Technical Workflow to Safely & Effectively Deliver Gene Therapies via ICM Administration

  • Leveraging intra-cisterna magna (ICM) delivery to maximize vector distribution throughout the CNS
  • Key technical and clinical considerations for precise and reproducible administration to the cisterna magna
  • Evaluating neuroimaging strategies to guide and confirm targeted delivery
  • Exploring scalability, safety, and dose optimization for broader clinical application in genetic CNS disorders