Challenges & Opportunities in Treatment of CNS Tumors
11:30 am - Thursday 3rd December 2026
- CNS tumors, including newly diagnosed glioblastoma (GBM) and brain metastases, represent a significant commercial opportunity in an area of urgent unmet medical need. The incidence of brain metastases is increasing, in part because advances in treatment for cancers such as colorectal, pancreatic, breast, and lung cancer are extending patient survival and allowing more time for disease to spread to the brain
- Many promising anticancer molecules are under development, but achieving effective concentration without causing toxicity remains a daunting challenge because of the blood brain barrier
- We compare several strategies for drug delivery to the brain for the treatment of CNS tumors, delineate their respective advantages and limitations, and assess the outstanding challenges that remain to be addressed, including technical, adoption-related, and supply chain-related barriers
